Welcome to Dr. Kate Kraus Brilakis' Learning Portal
review question: list the two primary components of blood.
blood
1. Leukemia
review question:
the process by which red blood cells are made is called _________________________.
agranular leukocyteshave few or no granules.
Monocytes and lymphocytes are agranular.
B & T lymphocytes (B cells/T cells)
defend the body against specific pathogens and as such confer specific immunity.
each RBC contains 270 million hemoglobin molecules...
each can carry four oxygen molecules.
anti-A, anti-B and anti-Rh
antibodies are impregnated on the card.
Blood added to the card will clot if the blood exhibits antigens
on its cell surfaces which bind to the
antibodies on the card.
Blood Analysis: Pathology
6
review question:
the primary purpose of WBCs is to ___________________.
fight parasitic infections
let's look
at RBCs
let's look
at WBCs
blood cell antigens are recognition proteins which determine blood types
immature RBCs have a nucleus.
as they mature, they enucleate.
the ejected nucleus is engulfed by macrophages. this adaptation allows red blood cells to maximize their oxygen-carrying capacity by fitting in loads of hemoglobin and increases the RBC's flexibility to get through narrow capillaries.
review question: what are the three types of blood cells?
blood compositon
release histamine/heparin
someWBCs contain granules
Granules
are tiny vacuoles containing enzymes used to defend against pathogens, reduce inflammation and destroy cells.
Granulocytes are part of the
innate immune system
human blood
Hemoglobin is composed of 4 protein subunits and four iron-containing heme groups.
Rh antigen determines
blood type
(+) or (-)
3. Pernicious Anemia
how is a scab formed?
5
review question:
some white blood cells are granular. What is the purpose of granules?
review question:
a person who is type A blood is given type B blood in a transfusion by mistake. A clot forms. Explain why.
review question:
explain what determines that a person is type B+ blood type.
type A type B type AB type O
blood type test
Rh antigen absent = (-)
fight bacterial infections
Parasitic Infections:
5. Plasmodium
6. Trypanosoma
phagocytes fight
bacterial infection
watch this short video explaining hematopoiesis
Rh antigen present = (+)
Blood is composed of plasma, red blood cells, white blood cells, and platelets. It transports essential substances and helps maintain bodily functions. Plasma makes up about 55% of blood volume, while the other components constitute the remaining 45%
summary
blood plasma antibodies are the opposite of the blood cell antigens
fight viral infections
what is hematopoiesis?
review question:
T cells and B cells belong to the agranular category of __________________.
review question:
what type of molecule is hemoglobin? What is the function of hemoglobin?
review question:
on the blood type identification card, what would cause each of the four circles to look the way they do? What do they tell you about the person who donated the blood sample?
4. Eosinophilia
2. Sickle Cell Disease
antibody serum used to test for agglutination
watch this short video showing neutrophils looking for pathogens.
Eldon card